Chapter 1032 Will It Rust?
On the second day after the operation, Brian's drainage tube and urinary catheter were removed, and he began to get out of bed with a waist belt. He was very satisfied with the results of the operation.
Some researchers in the laboratory often come to chat with Brian when they are free. Of course, the topic of these people's chats is still academic. Anyway, as long as they chat for a few words, they can get into the academic topic. Especially Lu Xiaolu is a rare genius, and his comprehension is far beyond that of ordinary people. After communicating with Brian, a master who stands at the forefront of academics, he has benefited a lot and solved many problems.
In the research on tumors, Yang Ping's current idea is to use M13 bacteriophage as a carrier to carry the K factor that can kill tumor cells into the human body, and then selectively affinity with tumor cells, and then kill tumor cells. This idea is very good, but the specific operation is difficult.
Among them, embedding the K factor into the M13 bacteriophage is a difficult problem, and secondly, making this complex selectively affinity with tumor cells is another difficult problem.
The system space can only provide time, space and materials, but cannot provide ideas for solving problems, so Yang Ping has to think about how to solve the problem himself. Yang Ping proposed an idea, and now many specific technologies are needed to realize this idea.
In immunology, especially in the field of tumor immunology, Brian can be said to be the most advanced in the world, and some of his specific experimental methods can be used as reference.
The sea is open to all rivers, and it is great to be tolerant, this is the attitude of doing academic research.
The electronic reading screen is hung with Brian's postoperative MRI photos. Although the metal implants have some interference with the image, the details of the surgical area can still be seen clearly. The huge prolapsed intervertebral disc nucleus pulposus has been removed, and the compression of the nerves has naturally been relieved. The lumbar spondylolisthesis has been reset, and the lumbar 4 and lumbar 5 vertebrae are firmly fixed by pedicle screws. In the future, the lumbar 4 and lumbar 5 vertebrae will fuse together, and the two fractures will become one bone, and this segment will also gain lasting stability. Of course, this stage also loses its own mobility, but there are five lumbar vertebrae, and losing the mobility of one segment will not cause much loss of the mobility of the entire lumbar spine. There is almost no effect on the elderly, but there is still an effect on young people, who have higher requirements for waist movement.
"Professor, if there is no lumbar instability, but only simple lumbar herniation, can we choose a combination of disc removal + intervertebral bone fusion + pedicle screw fixation?"
"Yes, many young and middle-aged people now only have lumbar disc herniation. Can we only do disc removal?"
The students around raised their doubts.
"If it is a young and middle-aged patient, there is no lumbar segmental instability, then this combination of procedures cannot be chosen in the procedure, and only lumbar disc removal should be done. Now a large number of samples show that the effect of only lumbar disc removal is very good." Yang Ping explained to everyone.
Brian wore a waist belt and a walker next to him. In fact, he can walk by himself, but he asked the caregiver to follow with the walker. If he gets tired, he can take a rest with the walker handrail.
Brian didn't know how to read an MRI film, but Mannstein had shown him several times that he understood a little bit. He couldn't see anything else, but at least he could understand two things. One was that the huge nucleus pulposus was a black thing on the MRI film, but now it's gone. The other was that the front and back edges of the two vertebrae were originally staggered, but now they are on the same line, and it's obvious that they have been restored to the correct position.
Curiosity made Brian think a little bit. In fact, the saying "different fields are like different mountains" is more prominent in English-speaking countries than in China. In the Chinese world, as long as you know the characters, you can understand a little bit even in books on other majors. At most, you don't understand the meaning of some professional terms, but you can still understand the basic content of the expression.
But in the English world, as long as you jump to a major that you have never been exposed to, even a professor like Brian can't understand anything. This kind of incomprehension is really incomprehensible, not understanding at all, all you see are letters.
This is like beef, dog meat, and pork. In Chinese, even if you know them, at least you know that it is meat, and it is animal meat. In the English world, you have no idea what it is. So it is not surprising that many high-level intellectuals in the English-speaking world do not know how to say a cuboid, and do not know what a cuboid is when they see the word.
"If I bend over, will this metal screw break inside my body?" Brian was worried about this.
Yang Ping told him: "It is possible, but it is very unlikely."
"What if it breaks inside?" Academics like to get to the bottom of things.
"The function of these metal fixations is temporary fixation, that is, before the two vertebrae grow together, the stress is shared by the metal internal fixation. Once the vertebrae grow together, its function is completed. Therefore, this problem can be divided into two situations. If the screw breaks after the vertebrae are fused, the screw can be taken out. If the vertebrae have not yet fused, then you can only do another operation to replace the broken internal fixation with a brand new internal fixation and fix it again." Yang Ping satisfied his curiosity.
"What if the screw breaks inside the vertebrae, like it is buried inside, how to take it out?"
It seems that Brian is studying this problem as a serious academic issue.
It is also a good way to let everyone see how a Nobel Prize winner thinks about problems, and at the same time let everyone know that no professor is an authority. They are all human beings and must have their own cognitive limitations. There is no authority in the eyes of real scientific researchers. , must have the awareness and ability to question.
Yang Ping pointed at the internal fixation on the screen with the pencil's eraser end: "If it's broken inside the vertebrae, there's no need to remove it at all, just leave it in. But if you want to take it out, it's not impossible, it's just a little more troublesome. It's okay. This is necessary.”
"If metal stays in the body for a long time, won't the released metal ions enter the blood? And then spread around in the human body? Will it not affect physical health?"
The more Brian asked, the more curious he became, and he was already immersed in this kind of thinking.
Yang Ping told him slowly: "The question you asked is very meaningful. This is also the biggest potential risk of metal-on-metal artificial hip joints at present. A large amount of metal ions enter the human blood, which has unknown potential risks, such as causing cancer. But This exists in metal-on-metal artificial hip joints, because the friction between metal and metal will cause a large amount of metal debris to fall off, and a large amount of metal ions to enter the bloodstream. However, the situation you are worried about about the broken screws in the vertebrae just mentioned does not exist. The metal left in the vertebrae has no friction and is surrounded by bone. It can be considered as an inactive piece of metal. There is no large amount of metal ions entering the blood, so it can remain in the body for life. "
Brian was thoughtful, as if he didn't understand.
This was all common sense to a spine surgeon, but to Brian, he felt it was a momentous discovery.
This is not surprising, because this knowledge is in his blind spot. No matter how he thinks, he lacks corresponding thinking content. Without strong content to support, his thinking will appear pale and feeble.
"Will it rust? Or will it react chemically with ions in the surrounding bone tissue? If a chemical reaction occurs, can it be controlled?"
Brian touched his chin and raised the question seriously.