Chapter 1054: Tenacious Vitality
In fact, Zhang Chunquan from the Whitehead Laboratory in the United States had visited Nandu Medical University before visiting Peking Union Medical College. He proposed to meet Yang Ping, but was directly rejected by Yang Ping. Whether from an emotional or interest perspective, Yang Ping thought it was unnecessary to meet him, and meeting him was a pure waste of time.
To be honest, the purpose of cooperation is to learn from each other's strengths and weaknesses and achieve a win-win situation. To put it bluntly, it is to use each other and take what each needs. Now Yang Ping can be said to be the world's number one in the field of stem cell research. He is one dimension ahead of other research teams, so now he does not need to cooperate with other laboratories. These so-called cooperation and sharing will only benefit others.
When Yang Ping's stem cell research was not yet established, the laboratory where Zhang Chunquan worked would even refuse Chinese people to visit, on the grounds of preventing the leakage of cutting-edge technology. Now they have proposed that science has no borders and work together to contribute to the progress of human medicine. This is not a joke. They are always right. They speak so high-soundingly, but in fact, it is all for the sake of interests.
When they have an advantage, they talk to you about intellectual property rights and confidentiality; when they are at a disadvantage, they talk to you about science without borders and cooperation.
Yang Ping didn't buy it. In his eyes, cooperation was a naked exchange. If there was no equivalent to exchange, there was no point in talking.
"Xiao Yang!"
Yang Ping had just returned from Nandu Medical University and received a call from Professor Liang.
"Professor Liang!" Yang Ping hadn't contacted Professor Liang for a while.
Professor Liang was in a good mood these days. He knew about this. Song Yun had told him about it. Originally, Professor Liang had given up on Zhang Chunquan's affairs, and the knot in his heart had long been untied.
But Zhang Chunquan did provide some help to some laboratories when he returned to China this time. This made Professor Liang very pleased, thinking that he had misunderstood Zhang Chunquan. He originally refused to meet Zhang Chunquan, but finally agreed to meet. The master and apprentice met again, and Professor Liang was very excited.
When Zhang Chunquan asked Professor Liang to help him with his cooperation with Yang Ping, Professor Liang finally understood that his previous cooperation with other universities was just a prelude. In the end, he still wanted to cooperate with Yang Ping, but was rejected by Yang Ping. Therefore, the cooperation with Yang Ping was in a dilemma. He wanted to make a breakthrough by using the relationship between Professor Liang and Yang Ping. The so-called visit to the mentor was just for the use value of the mentor.
For more than ten years, let alone visiting the mentor, he didn't even write a letter to the mentor. Now he suddenly visited the mentor with great fanfare. How painful it was for Professor Liang at this time.
Yang Ping knew about Zhang Chunquan's return to China this time. He had sent people to contact Yang Ping before, but was rejected by Yang Ping. He wanted to contact Yang Ping several times, but was also rejected by Yang Ping. Later, because Yang Ping was busy with other things, he didn't pay much attention to him. Unexpectedly, he ran to Professor Liang.
Professor Liang was silent for a moment on the phone: "Xiao Yang, Zhang Chunquan didn't come to see you, right? You must stay awake at this time. Whether it's him or anyone else, there will be many temptations thrown at you now, you must stay calm."
"I understand, thank you Professor Liang for reminding me, he has come to me, but I haven't met him, I don't want to see him..." Yang Ping explained clearly on the phone why he didn't see Zhang Chunquan, so that the old man wouldn't worry about him.
After listening, Professor Liang was relieved. He no longer worried that Yang Ping would be tempted and make some stupid decisions. Yang Ping's maturity in this regard exceeded Professor Liang's imagination.
Yang Ping reported some of his recent research to Professor Liang. Professor Liang was stunned after listening. He didn't expect that after a period of no contact, Yang Ping ran a long way again. He actually achieved great results in the treatment of osteosarcoma. The method he used was brand new. He had never heard of it before. What K factor, what carrier virus, what to start the apoptosis program of tumor cells, all of which are world-class. This level is not comparable to Zhang Chunquan. It seems that our real top talents are still serving the motherland and have not been lost.
——
As for Zhang Chunquan's visit, if Professor Liang hadn't mentioned this, Yang Ping wouldn't have time to pay attention to him. Yang Ping wasn't worried that Professor Liang would be sad because of this, because Professor Liang had been sick for Zhang Chunquan, and now he should have seen through everything and wouldn't have any more emotional fluctuations.
These days, Yang Ping went to Ruixing Company and Nandu Medical University every other day. Professor He's team has developed a biomedical image recognition engine. This engine doesn't need big data to feed it. It operates based on digital humans and uses normal cells in digital humans as a reference. It has many modules. The module developed now is the recognition of cell images under electron microscopes. It can automatically compare each image with normal cells of the same type. The images with differences will be kept for the next step of recognition, so that the requirements of experimental views can be met step by step.
Yang Ping handed the remaining electron microscope images that had not been viewed to this intelligent engine for viewing. It was very fast. It took only a few minutes to read all the images and successfully found three images. These three cell images had the structure of K virus, indicating that they had successfully infected tumor cells.
The experimental team is still observing Sisi's dynamics. Almost every few days, they have to puncture her metastatic tumor to obtain live cells. In the second batch of electron microscope images of live cells obtained by puncture, they finally found a tumor cell in a state of apoptosis. Although there is only this one, it is a question of existence or non-existence, a question of 0 to 1. Now it can be basically confirmed that the K virus can not only infect Sisi's tumor cells, but also activate the apoptosis program of tumor cells.
After confirming these two points, Yang Ping is more confident about this experiment, which shows that the general direction of this experiment is correct.
According to Yang Ping's philosophy: do things right first, then do things well. Now it seems that things have been done right, and the next work is to do things well.
Based on this result, Yang Ping speculated that after the K virus passes through the human immune system, the number of viruses that reach the tumor is very small. Now the main work is to improve the structure of the virus so that they can pass the immune system smoothly, and they must continue to maintain the ability to infect tumor cells and activate the apoptosis program of tumor cells. The latter is the most important. Without the latter, even if the virus can escape the human immune system in large quantities, it will be useless.
There is still a lot of work to be done, such as improving the detection method. Now it relies on puncture to obtain tumor cells and put them under the electron microscope for observation, but it is impossible to use this method when it comes to actual treatment. This method is only suitable for initial experiments, so a matching detection method needs to be developed in the future. Blood can be used to detect the number of virus-infected tumors and the number of tumor cell deaths. This is a difficult task and will be done slowly in the future.
Yang Ping’s current thinking about scientific research is also correct - make full use of computers, not simply use computers to assist scientific research, but use artificial intelligence technology as a basis to develop various auxiliary tools to maximize the role of computer assistance, not only to liberate manpower from heavy work, but also to improve work efficiency by thousands of times.
For example, if you rely on manpower to identify images under an electron microscope, it will take a long time even if everyone works day and night, but with the help of a computer, you can read all the images in a few minutes. Although the accuracy will not be ideal at the beginning, it will become more and more accurate if the model is improved slowly.
In fact, Yang Ping now thinks that the system strike is not a bad thing, but a good thing. When there was a system to help before, Yang Ping would definitely not rush to develop these computer-assisted tools, such as artificial intelligence and image viewing engines. After all, the demand is not very large, and the sense of urgency is not very strong.
Now that Yang Ping has no system, he is eager to create a "system" again. This system is computer tools. Although these tools are very crude now, they will be very useful intelligent tools in the future. These tools can not only be used by Yang Ping, but also by others, and can contribute to the entire scientific research community.
Now Yang Ping wants to pull scientific research from the "manual work era" to the "industrial era", and the value of these computer tools is undoubtedly equivalent to the "steam engine".
In order to cooperate with Yang Ping's experiment, Director He's team has to develop various computer tools. In fact, these researchers in the laboratory have very good brains. Many of them are passionate and have enough curiosity about new things, so they like to study these new things. However, because of their commercial tasks, it is difficult for corporate researchers to make new things that are not related to commercial tasks.
The classic programming language C language and the operating system UNIX operation were developed from Bell Labs in the past, and they are still widely used today.
Ruixing Group has also established an artificial intelligence research institute and a specialized artificial intelligence technology company. This company and the research institute will cooperate with Professor He's team, so that the strength of the entire large team will be enhanced, and it will be easy to develop these tools.
Huang Jiacai spent a lot of money to recruit a group of top talents in artificial intelligence, integrated and acquired some technologies and Professor He's digital people, and developed artificial intelligence models.
——
Sisi gradually recovered from the first experiment. In fact, the situation at that time was still quite dangerous. The high fever of 42 degrees lasted for so long, and any antipyretic medicine was ineffective. The heart rate was so fast that the whole body could collapse in the high fever at any time.
Everyone was very anxious at that time. Yang Ping kept telling himself that he must stay calm and rational, so he behaved extremely calmly throughout the process to ensure that he did not make mistakes. In that situation, a small misjudgment would cause irreparable serious consequences.
In the ward, Yang Ping saw Sisi fiddling with her cactus again. She looked much better than a few days ago, but after escaping death, it can still be seen that the high fever caused by the virus at that time left marks on her body. Her lips were cracked, her face was very bad, and the whole person was very weak.
"Professor Yang, do you think this cactus is amazing? It looked like it was dying once before, and all the exposed parts were eaten by insects. I thought it was going to die, but then I changed the soil for the remaining cactus and paid attention to killing insects. It slowly came back to life and is growing well now. So I admire it very much and always put it in my room. I feel that I will be able to survive like it." Sisi said to the cactus.
No wonder the little girl always brought her cactus with her every time she was hospitalized. There is also a story like this, and it is a very positive story.
"Don't you think so?" Sisi asked Yang Ping.
Yang Ping looked at the pot of cactus. Now it is hard to see the miserable state at that time. However, the vitality of cactus is indeed very strong. It can be said to be the most tenacious plant. It is not afraid of severe cold or drought. Just cut a piece of cactus and stick it in the soil and it will live. It can live well in the desert and release its greenness to its heart's content.
"Of course, so we don't have to worry at all. Although the process is tortuous, the future must be bright."
Yang Ping opened the painting in his hand and showed it to Sisi: "The data collected in the first experiment is very optimistic. Although we only found a few meaningful pictures, it is these pictures that confirm that the assassin K virus we sent out can successfully approach the enemy and kill it. It's just that most of the assassins we sent out this time were eliminated by the guards in your body, and only a few successfully infiltrated."
"What should we do?" Sisi widened her eyes.
"We need to modify the K virus again. The previous K virus and the source virus have a very different effect on the immune system. It is like a brand new virus. We need to modify it to be as close to the source virus as possible. This closeness refers to the interaction with your immune system." Yang Ping pointed to the drawings he drew and discussed with Sisi. He treated Sisi like a student.
Although Sisi's ideas were sometimes naive, Yang Ping would also discuss with him seriously, just like discussing problems with the world's top scholars.
"Wait a minute, I'll go wash my hands." Sisi looked very serious. He decided to have a good discussion with Yang Ping after washing his hands.
After washing his hands, Sisi spread the drawings on the table next to the bed: "Is it because the previous group of assassins were not well disguised and were discovered by the guards? Now we need to help him disguise again so that he can deceive the guards in my body?"
"That's it. We must not only disguise the assassin well, but also not weaken his ability to assassinate. We must take both into account and not lose one for the other." Yang Ping explained in a language that she could understand.
"I understand. When will the next experiment be done?" Sisi was looking forward to it. She didn't seem scared at all.
Yang Ping was stunned for a moment: "Don't be impatient. You just finished your first experiment. You must recover. Otherwise, it will be difficult to withstand the impact of the second experiment. We must prepare for the worst every time we do an experiment. We can't take it lightly."
"It's nothing, it's just a high fever. I was confused and didn't know anything at the time. When I woke up, I saw many faces around me." Sisi still remembered the high fever in her first experiment, but she was not afraid.