Chapter 1057 Accident

The independent ward is a newly opened ward of the Institute of Surgery. It was originally used as an ICU supporting the Institute of Surgery. All kinds of equipment have been fully equipped, and they are all the world's top medical equipment. However, the staff is temporarily not in place, so this ICU is temporarily Not put into use.

Now because of Sisi's experiment, Yang Ping selected the doctors and nurses who participated in the experiment to be stationed in this ward. This is equivalent to an ICU with elite medical care, and the only patient is Sisi, and the attending doctor is Yang Ping.

Sisi was lying in the ward. She suffered a cardiac arrest during the third experiment. After being rescued, her heart was extremely weak. The intracranial tumor seemed to have faintly exceeded the critical line, causing the heart to beat weakly. The two were intertwined. As a result, his heart is currently extremely weak, and he can only rely on ECMO to maintain his life, and cannot be taken offline for the time being.

With the support of ECMO, Sisi remained conscious to a certain extent. Yang Ping asked the nurse to place her cactus in the corner next to the bed to accompany her. Her parents saw their daughter through the glass every day, although they had already been mentally prepared. , but still heartbroken.

Yang Ping stood beside Sisi's bed and smiled at her: "Can you still hold on? We will win soon."

Sisi stretched out a hand to hold her fist and touched Yang Ping's fist. A smile appeared on her pale and dry lips: "Can you please help me handle your matter?"

That thing?

It's about body donation.

Yang Ping did not answer directly: "You have to ask me about this first. If I don't agree, then it won't be done."

"What?" Sisi was weak, and there was the sound of machines running next to the bed.

"I didn't even agree. How could you have a chance? Don't worry, things that I didn't agree with won't happen." Yang Ping grabbed Sisi's hand and said firmly and unquestionably. The little girl's hand was very cold and he turned his head. I took a look at my blood pressure and it was within the normal range.

"I believe in you. I see the strong confidence in your eyes. It's the same as the first time I saw you. This feeling can make everyone believe in you. This kind of look can heal everything." Sisi said calmly.

Yang Ping smoothed her hair that was floating on her forehead: "That's right. You have to trust your teacher. I told you to study medicine with me, and I will definitely be able to do it. Come on."

Sisi nodded.

Song Zimo next to him said: "Do you want to use sedatives?"

When using ECMO, even if the patient is awake, the patient is usually injected with some sedatives to put her in a sleep state. This facilitates care, reduces the patient's energy consumption, and reduces the patient's irritability and fear.

Yang Ping nodded and let the little girl sleep. This would reduce a lot of psychological pain.

After coming out of the ward, Yang Ping saw Dean Xia and Director Han in the doctor's office. They were also very concerned about Sisi's condition.

"Are you okay?" Dean Xia, who was waiting for Yang Ping, stood up from his chair, held Yang Ping's hand, and patted his shoulder.

Yang Ping looked a little haggard: "It's okay. There is no problem now under the maintenance of ECMO, but it is difficult to get offline."

"We won't go in to see Sisi for fear of disturbing her rest. If you need our help in coordinating, just ask. If you need help from other departments, just tell me directly." Director Han said.

Yang Ping nodded: "I will tell you in time if necessary."

Dean Xia and Director Han only came to express their importance to this experiment. They did not dare to stay for a long time for fear of affecting everyone's normal work. After understanding Sisi's condition for a few minutes, they hurriedly evacuated.

——

The fourth experiment is about to begin. This time Yang Ping goes into battle in person. He wants to experience for himself what it feels like after the K virus is injected into the human body. Except for Song Zimo, Xu Zhiliang, and the doctors and nurses participating in the experiment, no one else knows about it for the time being. Yang Ping doesn't want to let anyone know about it. Others worry.

If the news leaks out, Dean Xia will definitely not agree to it. With his style, even if Yang Ping demolishes Sanbo Hospital, he probably won’t think it’s a big deal. But if Yang Ping takes the risk to inject the virus himself, he will definitely He would not agree to anything, and he would probably ask the security guards to tie Yang Ping up.

I also said hello to Yang Ping at home, saying that I would stay in the independent ward for experiments this week and would not go back, and sometimes I might not be able to get through on the phone.

Yang Ping believes that the fourth modified K-virus is the best configuration and must have found a balance between safety and effectiveness.

Professor Zhang Zhiwei, who delivered the virus preparation, was stopped by the security guard at the door and not allowed to enter the ward. He was very puzzled. He could go in a few times before, but why he was not allowed in this time. But the security guard didn't know the reason. They just Act as ordered.

Professor Zhang heard that the little girl doing the experiment was admitted to the ICU and was in critical condition. She relied on ECMO to maintain her life. The little girl's life might be in danger after the fourth experiment, so other staff were not allowed to enter the ward to see the tragic scene. Professor Zhang Zhiwei did not continue to inquire, and went back after delivering the virus preparation.

Yang Ping was lying on the hospital bed, with Song Zimo, Xu Zhiliang, and Xia Shu beside him. The nurse's hand holding the syringe was a little trembling, and she didn't know whether she should inject or not.

"Don't be afraid, just get the injection!" Yang Ping encouraged the nurse.

The nurse felt uneasy and mustered up the courage to slowly push the virus into Yang Ping's blood vessel. Everything was calm and nothing happened.

While Yang Ping was dictating his feelings, Song Zimo was recording beside him. He didn't feel any discomfort now.

Half an hour later, Yang Ping began to feel his body was hot. The nurse hurried to take his temperature and found that Yang Ping began to have a low fever. The nurse measured her temperature every half an hour. In order to ensure the accuracy of the data, in addition to using an ear thermometer to measure the ear temperature, the original mercury thermometer was also used to measure the armpit temperature.

Yang Ping's body temperature was gradually rising, about one degree every two hours. By the evening, the body temperature had risen to 42 degrees, and sometimes it would exceed 42 degrees.

Under high fever, Yang Ping's whole body was shivering, and it was particularly uncomfortable. It was as if his body was being torn and reorganized. In a daze, he felt that his body was suddenly very big, and suddenly very small, like a balloon being scaled. Now he understood how strong the will of this little girl Sisi was.

Although he was dazed, Yang Ping could still maintain a vague consciousness and was not completely unconscious.

Under high fever, his heart rate also began to speed up. In fact, the increase in heart rate is the most dangerous. The heart can easily collapse under high load.

Various instruments beside, including ECMO, were ready to save lives at any time. Song Zimo, Xu Zhiliang, and Xia Shu were all standing by. They took turns on duty and guarded the bedside 24 hours a day.

The high fever lasted for 3 days and then slowly subsided. During the whole process, Yang Ping was not completely in a coma. Even at the most serious time, he had a trace of consciousness, but it was a vague consciousness.

Blood was drawn three times a day and sent to the Virology Laboratory of Nandu Medical University for examination, but they called to ask: Is there any problem with the experiment? Is there any program wrong? Why didn't the virus titer gradually decrease, but gradually increased, then decreased, and finally maintained at a horizontal line.

This is completely inconsistent with common sense. The injected virus is a virus that cannot replicate. One less dead means one less. Logically, after three days of immune confrontation, there should be very few viruses left. This was the case for the first three experiments.

Why does the virus titer change curve look like a live virus that can replicate?

In order to confirm, the nurse drew a few more tubes of blood from Yang Ping this time. In order to prevent any problems on the way, Lu Xiaolu and two doctors were sent to deliver the blood specimens this time.

The test results surprised Yang Ping and all the people involved in the experiment. The virus was not cleared by the immune system, and the number increased. Could it be that they successfully replicated in the body? How could it be possible? The virus had its replication gene knocked out.

In order to solve this mystery, Professor Zhang Zhiwei immediately sent the virus to the genetics laboratory for gene sequencing.

Indeed, the gene sequence of the virus was complete, that is, the replication gene that was knocked out had been supplemented. This is impossible and violates the current biological laws.

This result made Yang Ping very puzzled. There are two possibilities. One is that the virus may really repair itself in the body and restore its replication gene. The second possibility is that when the virus sample was cultivated, K virus without knocked out genes was mixed into the virus sample. These viruses have the ability to replicate. Other castrated viruses have died under the attack of the immune system, but these viruses not only survived through replication, but also proliferated in large quantities.

I didn't expect such an accident to occur in this experiment. As for the reason, it will not be found out for a while. Now the top priority is to remove the virus in Yang Ping's body, otherwise it will be a big trouble.

The experimental team was all anxious. Now Yang Ping was carrying the virus, which was equivalent to being infected with a new viral disease. If the immune system could not eliminate these viruses, they would remain in the body for life.

However, what surprised Yang Ping was that these viruses did not react at all in the body. Could it be that they coexisted with his immune system?

With this question, Yang Ping asked the nurse to draw blood from him again, and then took the sample to the virus laboratory of Nandu Medical University for observation. He himself did not dare to leave the isolation ward of the independent ward. At present, it was unknown whether the virus in his body was contagious. If it was contagious, how did it spread? When the virus laboratory could not make a conclusion, Yang Ping could only be isolated.

Soon, the analysis conclusion of the virus laboratory came out. This virus was not contagious because they were very fragile. They died in a few seconds when they were separated from the blood and body fluids of the human body. They could not survive in the extracorporeal environment, including the air.

This at least made Yang Ping feel much more at ease. If it was not contagious, then at least it would not cause danger to others, and the danger would also be on himself.

There is also a very special phenomenon. When the virus taken out of Yang Ping's body is cultured in vitro, the K factor will be lost in the second generation of viruses, that is, they will become ordinary viruses and will not have the function of K virus.

Professor Zhang Zhiwei believes that the K virus in Yang Ping's body has now mutated and has become an independent species. This species can only survive in Yang Ping's body for a long time.

In order to verify this conclusion, Professor Zhang Zhiwei decided to use experimental monkeys to conduct some experiments. He extracted blood with viruses from Yang Ping's body and injected it directly into the monkeys. These viruses magically lost their ability to replicate in the monkeys and were slowly killed by the immune system.

These viruses can only survive in Yang Ping's body. Could it be that they have reached some kind of tacit understanding with Yang Ping's immune system? This is a branch of the experiment. Not only Yang Ping himself is interested, but also Professor Zhang Zhiwei is interested.

In order to verify whether this accident is replicable, Professor Zhang Zhiwei conducted experiments on monkeys. Without exception, these viruses did not react in the monkeys and all died, even if the replication gene was not knocked out.

It seems that Yang Ping was right to enter clinical trials directly, because the monkey's immune system is completely different from the human immune system, especially in the process of evolution, the viruses that humans are exposed to are completely different from the viruses that monkeys are exposed to in the jungle, which determines that humans and monkeys react completely differently when facing some new viruses.

The virus in Yang Ping's body is likely caused by a very low probability mutation. If it is a mutation, it is impossible to replicate such a low probability event.

Professor Zhang Zhiwei also developed a strong interest in the virus in Yang Ping's body. In fact, many major scientific research in history was produced in accidental events, such as the production of penicillin, which was somewhat accidental.

Since the virus in his body is not contagious and has not caused any negative impact on him for the time being, Yang Ping is not too worried for the time being. He will slowly study ways to eliminate it later when he has time.

He has not been back for a few days, so he called Xiao Su to report his safety.

Yang Ping now wants to study what happens when the virus in his body is injected into another person's body. From the speculation, it should no longer have fierce immune confrontation, and it can be compatible with the human immune system.

But there are risks. These viruses will remain in the body, and it is not known what negative effects they will have after they remain in the body.

"Or, let me try it." Professor Zhang Zhiwei is eager to try, because these viruses, whether theoretically or clinically verified, will cause high fever, but not life-threatening. Now the two volunteers participating in the experiment are safe and sound, and even Yang Ping looks very energetic now.

"You can try it if you want."

After personal experience, Yang Ping is now very sure of the temperament of this virus, and nothing serious will happen.

Mr. Li Ke, a once famous old Chinese medicine doctor, is very good at using the traditional Chinese medicine aconite to treat difficult and complicated diseases. Aconite is a toxic traditional Chinese medicine. Ordinary doctors dare not use it casually, let alone use it in large quantities, but Mr. Li dares to use it. He has used aconite to cure many difficult and complicated diseases.

Why does he dare? Because he had tested poisons on himself and took aconite himself to see what would happen if he took a certain amount of aconite. In this way, he thoroughly mastered the characteristics of aconite through his own testing of poisons and used it with ease.

On the premise of ensuring a certain degree of safety, Yang Ping agreed to let Professor Zhang Zhiwei try it.

PS: The last chapter was indeed a bit chaotic, including this chapter, which was not very good. I will slowly recover later, thank you! It is not finished so soon, and there are still a few major events that have not been written.