Chapter 1018 It’s a Misunderstanding, Wife!

Yang Ping was very relieved to have Lu Xiaolu as the director of the tumor laboratory. Lu Xiaolu's research field itself is the basic research of tumors, and this person is indeed a rare talent. The achievements he made in the past were obtained under a state of depression. Now that his body and mind are completely liberated, it is easier to achieve scientific research results.

After returning home from get off work, Yang Ping played with his son for a while. After changing his diaper, he held him in his arms and told him what surgery he had done in the hospital. The boy didn't cry or make a fuss. He smiled and kicked his limbs excitedly.

Xiao Su was working out in the gym at home. Her postpartum recovery was very good. Yang Ping's mother and Mrs. Su were cooking together in the kitchen. Professor Su and Yang Ping's father were chatting in the living room. It seemed that they were commenting on a war movie. The family got along very well.

The advantage of having a system is that you can start working at any time. After Yang Ping told his son a story, he put him in the crib. The little guy blinked his eyes. Maybe he was tired. He fell asleep after blinking a few times. At this time, Xiao Su finished working out.

"I'll look after him. You take a rest." Xiao Su said.

"I'll just take a nap here." Yang Ping said.

Xiao Su knew Yang Ping's habits. He liked to use fragmented time to rest, so he was as energetic as a cow all day long.

Yang Ping took a nap on the chair in the bedroom. He did what he said. He used his spare time to enter the system space laboratory and bought various equipment from the system mall according to the needs of the experiment. Soon all the hardware needed for the experiment was built.

To use M13 bacteriophage to carry K factor, it is necessary to first study the structure and function of M13 bacteriophage. Only by studying it thoroughly can we better transform it and make it work for ourselves.

Through the special camera system of the electron microscope, M13 bacteriophage appeared on the electronic screen, showing a unique and charming shape.

From the morphological point of view, M13 bacteriophage appears slender and uniform, like a delicate line, and the ratio of its length and diameter makes it extremely eye-catching under the microscope. The shell is composed of the main coat protein p8, which is tightly arranged together to form a protective layer of the phage. Under a microscope, you can clearly see these layers of protein structures, which are arranged in an orderly manner to protect the internal genetic material of the phage.

For the first time, Yang Ping felt that the microbial structure assembled by this protein was so beautiful. Yang Ping couldn't help but sigh at the precision and beauty of the organism. It even looks more harmonious and beautiful than any man-made machine.

The activities of M13 phages are also very distinctive. When they encounter suitable host cells-such as E. coli containing F plasmids, they will show their infection ability. Under a microscope, it can be observed that M13 phages attach to the F pili of E. coli through their secondary coat protein p3, which is the first step of infection. Once attached, the M13 phage will begin to transfer its D NA is injected into the host cell.

After the DNA is injected, the M13 phage will use the resources of the host cell to replicate. Under the microscope, it can be observed that changes begin to occur inside the infected cells, and new phage particles are gradually assembled inside the cells. This process is essential to the life cycle of phages and is key to their reproduction in nature.

It is worth noting that after infecting host cells, M13 phages do not cause host cell lysis like some phages. Instead, they secrete new phage particles from infected cells, while host cells can continue to grow and divide. This characteristic makes M13 phages unique in biological research. But for Yang Ping, this is not an advantage, but a disadvantage.

The electronic screen continues to live broadcast the morphology and activity of M13 phages under the microscope , it is like a fascinating journey of exploration. Their exquisite structure, unique infection mode and unique life cycle all show the wonders of nature and the charm of biodiversity.

Such a simple virus is so exquisite, so you can imagine how exquisite the complex human body is.

Looking at the bacteriophage on the screen, Yang Ping fell into thought. He couldn't wait to complete the whole experiment quickly. He didn't expect that pushing it back to start over would actually open up a whole new world.

If it is transformed into a killer that can infect tumor cells, they are not infecting E. coli now, but are precisely adsorbed on the outer membrane of tumor cells, and then through the long filamentous tail, what is injected is not only DNA, but DNA and K factor. K factor begins to work inside the cell, initiating apoptosis of tumor cells, and DNA allows the bacteriophage to divide and grow its strength.

If the M13 bacteriophage can be transformed according to the target, it will show unique characteristics. They are no longer simple parasites, but become "intelligent warriors" that can actively attack tumors. This process involves precise genetic engineering, which enables these tiny organisms to play a vital role in the battle against cancer.

However, the process of transformation is destined to be difficult and complicated. The process of transforming M13 phage is complex and delicate.

First, it is necessary to determine which genes or proteins need to be modified or added to achieve the anti-tumor effect, which usually involves precise editing of the phage genome, including inserting, deleting or replacing specific gene fragments.

But for Yang Ping, it is obviously not necessary to be so complicated, because he has mastered the K factor that initiates tumor cell apoptosis. He only needs to combine the K factor with the adhesion protein on the surface of the M13 phage, and then let the phage recognize and contact the tumor cells. The rest of the work is a matter of course. If it is done more advanced, the K factor is mixed with the DNA inside the phage, and after the phage infects the tumor cells, the K factor mixed with DNA is injected into the tumor cells.

The K factor can initiate the apoptosis of tumor cells and eventually kill them. In this process, DNA can also waste and utilize the substances inside the cells to split and strengthen the phage itself.

After designing the experiment, Yang Ping handed it over to the laboratory's manipulators to complete the rest of the work, allowing them to continuously modify the phage, and then let the phage and the K factor conduct a pairing test. It is estimated that the M13 phage can obtain hundreds of millions of different phages through modification. Which one can adhere to the K factor and which one can recognize tumor cells is a huge trial and error project. Trial and error is the strength of the system space laboratory. Yang Ping handed it over to the automated equipment to complete it.

Coming out of the system space, Yang Ping yawned. Dinner was probably not ready yet. Xiao Su asked curiously, "How come you are so energetic after sleeping for just a while?"

"I'm thinking about a question." Yang Ping said.

"What question?" Xiao Su asked curiously.

"I'm thinking about how bacteriophages inject DNA into cells. The long tail of bacteriophages is like a thick tube. When it finds the cell it likes, it immediately locks it, then inserts its tail into the cell and injects DNA into the cell with force. I've been thinking about this question just now, so I'm getting more and more excited." Yang Ping has indeed been thinking about this question just now.

Xiao Su listened and heard that this description was getting more and more wrong. Then, as if he had realized something, he punched Yang Ping's chest muscles with his pink fist.

"You are so energetic! You're still thinking about injecting DNA after a whole day of surgery?"

"Wife, I was really thinking about injecting DNA into your body just now. Oh, no, I mean how bacteriophages inject DNA into cells." Yang Ping was so excited that he mixed up his words.

Misunderstanding, wife!

My thoughts are pure and I was really thinking about scientific research just now.