Chapter 1016: Outsiders

As for the wedding, Yang Ping and Xiao Su hardly worried about it. They went to work and took care of their children. Their work and life were not affected at all.

Originally, the couple wanted to have a simple wedding and didn't want to make it so complicated, but things didn't go their way at all. No matter what, they didn't agree with them to have a simple wedding. However, as long as they didn't have to worry about it, Yang Ping and Xiao Su spent some time on reshooting wedding photos, and didn't care about anything else. They didn't know how the wedding preparations were progressing.

Yang Ping went to work as usual every day. After a whole day of surgery, he sat down in the doctor's office to rest. Song Zimo reported that the second review results of Fu Xiaotao, a patient with Castleman disease, had come out.

Yang Ping has always kept this case in mind, because a questioning overturned the theory that has been recognized by the medical community. This made Yang Ping begin to realize that there is nothing that cannot be questioned and nothing that cannot be tried.

Song Zimo opened the outpatient system in the computer and retrieved Fu Xiaotao's examination data. Yang Ping reviewed them one by one and compared them with the results of the previous examination.

After Fu Xiaotao took sirolimus alone, the results of the second reexamination were better than the first time, and various indicators were better. According to this trend, Fu Xiaotao's Castleman disease can be cured in about one or two years. The results of the treatment proved that blocking the mTOR signaling pathway to treat Castleman disease is very correct, and the previously recognized pathogenesis of interleukin 6 is actually wrong.

This time allowed Yang Ping to adjust his thinking about his tumor laboratory. It was not that his method was wrong, but it was very likely that the entire direction was wrong from the beginning. If the direction was wrong, no matter how perfect things were done, they would not get the expected results in the end.

This confirms the saying: do things right first, then do things well.

During this period, Yang Ping thought about his tumor experiment. It was impossible to succeed by relying solely on the system. Now he had to rely on his imagination to solve the problem. Imagination is something that the system cannot provide. It can only provide time and resources.

In the history of human evolution, it is a long process for some microorganisms to coexist with humans, which cannot be done in a short time. The protein structure of K factor is regarded as a foreign object when it enters the human body and is attacked by the immune system. K factor does not have the possibility of self-amplification. Under the attack of the immune system, the only outcome is annihilation. If the investment is increased, excessive K factor can cause over-activation of the human immune system and cause life-threatening.

But why can some viruses exist in the human body for a long time, such as hepatitis B virus, HIV, etc., which can exist in the human body for a long time without being eliminated by the immune system, because they have the ability to self-replicate, and have the ability to self-learn to avoid the immune system, and inherit this avoidance ability in the process of iteration.

Thinking of this, Yang Ping had a flash of inspiration in his mind. Why get a virus, modify the virus to be harmless, and then chimera the K factor with the virus, and put the new "virus" into the human body, so that this new virus has the ability to fight the human immune system, and at the same time has the ability to kill tumor cells, and let this virus exist harmlessly in the body for a period of time, it can kill the resurrected tumor cells at any time.

After this bold idea came into Yang Ping's mind, Yang Ping immediately planned to redesign the experiment and began to study according to this idea. With the experience of treating Castleman disease, Yang Ping was more confident in his bold ideas. There was no need to worry about any consequences when doing experiments in the system space. The most serious result was just a waste of points, which was no big deal.

"Continue to take sirolimus?" Song Zimo asked.

Yang Ping nodded: "Continue to take it, check liver and kidney function every month, as long as liver and kidney function is normal, continue to take it until recovery."

"Okay." Song Zimo wrote it down.

Nothing special happened, Yang Ping returned to his office, turned on the computer to check new emails, and Professor Maninstein sent a new email.

"Dear Professor Yang Ping, hello. Your space-oriented gene research is very popular. Everyone has always believed that this is an epoch-making achievement. It will change medicine and the world. It is the first time that human organs have been successfully cloned in vitro. It is no exaggeration to say that it will usher in an era of independent organ cloning. In the future, the treatment of human organ failure will become cheap and easy. Replacing organs is as normal as replacing parts in a machine, and there will be no rejection reaction. Once in a private salon of mine, several Nobel Prize winners in medicine and biology proposed that they wanted to go to China with me to attend your wedding. They wanted to meet you, the great doctor, and become friends with you. In addition, we have a problem here- ——The case of a non-heart patient, he is the granddaughter of Mr. Bryan, the Nobel Prize winner in medicine. The poor little girl has not found a suitable surgeon yet, because no one dares to do this kind of operation. I have the audacity to recommend you to him without your consent. Please forgive me. The information of this case is attached. "

Professor Maninstein's friend, a Nobel Prize winner in medicine and biology, his granddaughter is six years old and is a non-heart patient. Her heart malformation surgery is very complicated, so so far, he has not found a suitable doctor for his granddaughter. He once went to the United States to find a doctor. American doctors have performed many similar operations, but after seeing his granddaughter, they could only shake their heads. The difficulty is greater than imagined.

The normal position of the heart should be in the chest, protected by the chest supported by the rib cage. However, the heart of an outsider is not in the chest. Instead, outside the chest, the whole heart is only separated from the outside world by a thin layer of skin. This There is no difference from being naked. The outline of the heart can be seen from the outside, and even the outline of the blood vessels on the surface of the heart is clearly visible.

Such an exposed heart would be fatal if any accidental impact occurred. Mr. Bryan had been trying to find a doctor who could operate on his granddaughter, but to no avail until Maninstein recommended Professor Yang from China to him.

Attached is a video sent by Professor Maninstein. In the video, Chelsea, a child from outside the body, is wearing a carbon fiber hard chest shield to prevent the heart from being exposed outside the body from collision in daily life. When taking off this After putting on the protective shield, if you lift up your clothes, you can clearly see the bulging and beating heart. The close-up video shows that there is only a thin layer of skin between the heart and the outside world.

Yang Ping stood at the door of the doctor's office from his office: "Everyone who is not off work, please come over here."

Everyone didn't know what was going on, so they all gathered in the director's office. The video was played repeatedly on Yang Ping's computer screen. Everyone stared at the screen hoping to see every detail. Xia Shu, a doctor in cardiology, was more interested in this case.

"This is a case in Europe. It is very rare. The operation is very difficult, and the technical requirements for postoperative maintenance are also very high. Everyone should come into contact with this kind of case. If you have time these days, you can check the information and discuss it. ”

Yang Ping told everyone.

"This is a cardiac malformation, the scientific name is Cantrell's pentad, which has five coexisting malformations - sternal cleft, substernal defect, anterior half-moon defect of the diaphragm, pericardial parietal defect communicating with the abdominal cavity, supraumbilical abdominal wall In defective umbilical hernia, it is the coexistence of these five deformities that causes the heart to be exposed through the skin. The operation is very difficult. The operation not only needs to correct the deformity, but also needs to put the heart back into the chest. When the heart is put back into the chest, it needs to be suspended. Problems such as straightening out the large blood vessels connected to it are even more difficult to solve with one operation.”

"What type of Cantrell's pentad is this?"

"Type one! All five deformities are present."

"In addition, the accompanying malformations include dextrocardia, double outlet right ventricle, ventricular septal defect, atrial septal defect and pulmonary valve stenosis. The difficulty in treatment lies in how to correct the malformation of the heart and reset the heart."

"We have no precedent of such a complex case involving an outsider."

"Do you know why our department is called the Institute of Surgery? Because part of the surgeries performed are research-based. We are the first to try something new. We are a department that combines research with clinical practice."

"There are not many operations in the country. There were probably more than ten cases in Fuwai and Anzhen in the past. I have never seen such a complicated surgery. The number of surgeries in the world is only about two hundred."

Everyone immediately started discussing this case.