Chapter 1002 Checklist Puzzle
On the huge conference table, checklists were spread out one by one. In order to prevent the wind from blowing the checklists away, Yang Ping asked the students to close the doors and windows of the entire conference room.
Yang Ping constantly adjusted the positions of the checklists, just like a child playing a puzzle. Through multiple adjustments, these checklists were not only arranged by time, but also classified by type. Then, different checks were sorted out according to the internal logical relationship.
''Don't move them. Is there any information? "Yang Ping is now completely immersed in the analysis of these checklist puzzles.
The doctor who just went to get the checklist said: "All here, he packed these checklists in a box every time he saw a patient, and he took a photo of each checklist for record."
This is a serious and meticulous person. Perhaps this seriousness can save his life. If there is no better way, according to the current literature statistics, Fu Xiaotao will hardly live for two years.
Song Zimo was a little nervous on the side: "Any findings? ”
'These are the objective and complete pictures of the entire disease that we can get. Let's see, if we take each outbreak as a local part, then from the local analysis, it is true that its pathogenesis is based on interleukin 6, but now you gather all the single outbreaks together, from the perspective of the entire disease process, is the interleukin 6 model still correct?" Yang Ping already had some new ideas in his mind.
When you analyze many things carefully and thoroughly, the results will be very different, because no one may have really analyzed them so seriously before you.
Song Zimo, Xu Zhiliang, and every doctor around them came closer to see, but they all kept a small distance, for fear that they would accidentally blow away a checklist because of their exhaled breath.
"Thank you to every doctor for doing their best to improve the examination and collect information. Many examinations have found vascular endothelial growth factor. Although there have been a few times without examination, the trend can still be roughly seen." Yang Ping walked around the conference table.
Song Zimo listened to Yang Ping's mumbling and read the vascular endothelial growth factor test sheets one by one in chronological order. He looked at its development trend from the whole disease process and then fell into the process of each onset. Indeed, it was not interleukin 6 that ran through the whole process, but vascular endothelial growth factor.
"Are you saying that vascular endothelial growth factor is the possible basis for the whole disease? Or the interleukin 6 model is wrong and should be revised to the vascular endothelial growth factor model?" Song Zimo couldn't believe what Yang Ping said.
The interleukin 6 model is the recognized pathogenesis of Castleman disease in the academic community. Now, with just one case and a pile of test sheets, it overturns a world-recognized model. This is too much of a joke, but this is Professor Yang, and Song Zimo has to believe it.
In fact, Yang Ping has spent a lot of time studying this case in the system space, and it is definitely not just a casual question now.
Yang Ping walked around the desk, then stopped, resting his hands on the conference table, staring at the test sheets, and spoke for five minutes: "We can try to block the pathway that triggers VEGF production and activates T cells to inhibit the occurrence of the disease! If the patient is willing, we will use the advantages of the laboratory to re-analyze his disease."
"Shall I talk to him?"
"No, I will talk to him in person."
Yang Ping felt that he seemed to have touched the true pathogenesis of Castleman's disease. After overturning the original theory, he felt that his theory could better explain Fu Xiaotao's condition. If judged according to the monism of diagnosis, his theory could explain more clinical symptoms than interleukin 6.
After the thread in his mind was clear, Yang Ping asked the students to take pictures of all the test sheets as he had just arranged them, and then take pictures of each test sheet separately. He hoped to draw a trend chart of the changes in these test indicators. This work was more tedious, but these doctors and masters were eager to do it.
Without wasting any time, Yang Ping and Song Zimo came to the Department of Oncology. Director Jiang went out to participate in a case discussion. Yang Ping and Song Zimo went to find Fu Xiaotao under the guidance of the attending physician.
Fu Xiaotao was not in a very good spirit, because he had only saved his life with high-dose chemotherapy not long ago. When he fell ill this time, he was hospitalized for the first time and used high-dose hormones to control the disease, and then used cetuximab for treatment.
In the past, after stopping hormones, the disease did not relapse so quickly. Perhaps this time it was not a relapse at all, but the disease was not under control. High-dose hormones only temporarily controlled the symptoms. Once the hormones were stopped, the disease continued to develop until this fatal outbreak.
"Professor Yang!" Fu Xiaotao climbed up from the bed with difficulty.
Yang Ping and Song Zimo helped him lean against the pillow to a semi-sitting position. Fu Xiaotao's parents had been waiting beside him. They were obviously unhappy, because after Yang Ping's consultation last time, not only did the condition not improve, but it was so serious.
However, Fu Xiaotao still believed in Yang Ping. He had checked a lot of information and knew the complexity of his condition.
Yang Ping didn't care about that and said to Fu Xiaotao: "We have thought more deeply about your disease and found that the existing treatment methods are simply incapable of curing your disease. We now want to use a new method for you, but the new method is for scientific research and has not been used by anyone else. It has certain risks, so we must get your consent."
"How can that be possible!" Fu Xiaotao's mother rejected it outright.
Fu Xiaotao's father said gently: "Let the professor finish his sentence. The new method must be experimental. Don't be disgusted when you hear about the experiment. Let's go out first and let the children talk to the professor."
Fu Xiaotao's father took his wife out so as not to interfere with the doctor's communication with his son. Fu Xiaotao's mother followed him out very unhappy.
"Professor Yang, don't worry, they don't understand. I am willing to sign and participate in the scientific research methods you just mentioned." Fu Xiaotao fully agreed.
Yang Ping told him: "After all, it is scientific research and there are certain risks. Can you accept it? And it is likely to fail again."
Fu Xiaotao smiled bitterly and said: "I know this disease myself, and there is no good way to cure it. Since there is no way, why not try new methods that may be effective now."
"And if we use the new method, we will draw your blood and do a lot of tests because we need to find out the changes in some biochemical indicators in your body." Song Zimo added to explain.
Fu Xiaotao was very determined: "It's okay, you make arrangements."
As a graduate student, Fu Xiaotao checked Yang Ping's thesis. He didn't know it unless he checked it. He was shocked when he checked it. This is an academic expert. How could such a powerful person have time to fool around with you, an ordinary patient? He must have known it well. He personally came to propose this experimental method, and his desire to survive made Fu Xiaotao firmly grasp this life-saving rope. If he usually wanted to, he would not be able to invite such a powerful person, but now that someone comes to his door, if he doesn't agree, then You will miss valuable opportunities.
And Fu Xiaotao always believes that doctors and patients are comrades-in-arms, and the common enemy is disease.
"Do you really agree? Do you want to discuss it with your parents?" Song Zimo reminded.
Fu Xiaotao shook his head: "No, I am an adult and I can make my own decision. If I discuss this with them, it will definitely not work. My dad is fine, but my mom will definitely disagree."
"Okay, if you agree, I will talk to the doctor here and transfer you to our department for treatment. All costs for the scientific research part of the treatment will be free, and you can also get certain subsidies." Yang Ping put the matter on the spot. Set it down.
"Thank you! It's settled, you can come to me to sign at any time." Fu Xiaotao was very determined.