Chapter 837 Special Investigation Report (4K)
Parkinson's disease is a common neurodegenerative disease that mostly occurs in the elderly population, with an average age of onset of around 60 years old.
As industry experts, Li Weijian and others know that the prevalence of this disease in Daxia is extremely terrible. The probability of people over 65 years old in Daxia suffering from this disease is about 1.7%...
An expert from West Sichuan Huaxi frowned and said: "The most important pathological change of Parkinson's disease is the degeneration and death of dopaminergic neurons in the substantia nigra of the midbrain, which causes a significant decrease in the DA content of the striatum and causes the disease.
At present, major research institutions at home and abroad have not mastered the exact cause of this pathological change, but based on clinical cases and years of analysis, most of us believe that this disease and genetic factors, environmental factors, aging, oxidative stress, etc. may all participate in the degeneration and death process of PD dopaminergic neurons."
"There are also factors such as brain trauma and smoking that may increase this probability. In our previous research meeting, most of the data showed that smoking is negatively correlated with the probability of getting this disease." An expert from Yanjing added.
"Yes, if the patient cannot control the symptoms through medication and psychotherapy, we need to consider DBS surgery, deep brain stimulation, globus pallidus or subthalamic nucleus destruction to relieve symptoms."
The experts discussed seriously. If Gu Qing and others were the patients, they would probably have been disappointed.
Unfortunately, there is no if.
Professor Chen, bearing the scrutiny of these industry leaders, nodded slightly to Gu Qing, and then said calmly and loudly: "Yes, Parkinson's disease is a long-standing problem. The Global Burden of Disease Research Report once pointed out that the number of Parkinson's disease patients in Daxia accounts for about 23% of the global Parkinson's disease population. According to the model, by 1030, it is very likely that about half of the global patients with the disease will be middle-aged and elderly people in Daxia.
In addition to shaking, another important symptom of Parkinson's disease is slow movement. In the late stage of Parkinson's disease, due to the unstoppable loss of neurons that release dopamine, the drug levodopa becomes less effective in treating symptoms.
And our starting point is not on drugs.
In a paper report published in the journal Nature, foreign scientists found that by selectively destroying the function of mitochondrial complexes in dopaminergic neurons in mice, they found that this dysfunction is sufficient to cause progressive Parkinson's disease-related motor defects, and the correlation between different types of motor function impairment and dopamine release in different parts.
This discovery gave us a breakthrough in our research.
In conjunction with other departments, we share resources while further studying the mechanism of neural transmission and the sensitivity of animal and human nerves to equipment, coordination frequency, and synchronization of some confidential data.
Our Applied Neurotechnology Laboratory of the Institute of Brain Science had some special achievements three years ago. In recent years, due to the sharing of the results of several major projects of the company, it has achieved minimally invasive implantation of brain-computer interfaces, allowing patients to communicate stably even in the case of hemiplegia and Parkinson's.
Even if the patient's special nerve activity is high enough and his physical fitness can support surgery, we can still perform more advanced treatments and replace the necrotic parts with mechanical parts. "
Professor Chen's calmness surprised a group of medical masters.
What is this kid talking about? Can he already do surgery?
Three years? Such rapid progress?
"I have been paying attention to this field. Why haven't I seen your application documents?"
A stern professor walked quickly to Professor Chen and asked in a questioning tone.
When hospitals conduct certain clinical medical experiments, they need to submit all clinical plans, including preclinical test materials, planned test sites, sponsors, instructions for conducting clinical trials, and all situations found in animal tests, to official agencies. They must be reviewed and approved by the institutional review committee, and the progress and results of clinical trials must be reported to official agencies once a year.
The professor who asked this question, in addition to being a medical expert at the Medical University, also works in related institutions.
So when this kind of problem occurs in his field, his first reaction is that he must get to the bottom of it.
Professor Chen looked at the old teacher who was walking towards him. The other party's aggressive appearance and the appearance of teaching plans in the department before were like two different people.
However, he did not retreat, but explained very naturally: "Our clinical trials are all under the full supervision of special departments, and these documents do not need to be reviewed by normal institutions.
If you have any objections, you can use your own authorized channels to understand the specific situation.
Of course, my personal suggestion is that you should investigate the specific situation of this project in a safe environment, because this project is still in a highly confidential state for the time being."
This set of words immediately tied the old professor to the spot.
Then Professor Chen, the head of the laboratory, continued: "Next, we can see a patient with advanced Parkinson's disease who has been treated by us. He has been diagnosed and treated in the affiliated hospital of Medical University and West China before, so some of you should still have an impression of him."
Seeing that Professor Chen was able to guide these masters of the medical community in Daxia, Gu Qing was relieved to retire.
At present, the brain-computer interface of the Applied Neurotechnology Laboratory of the Institute of Brain Science can display quite a few functions in this area. In addition to being able to decode working memory, emotion and movement integration, it can also perform adaptive regulation and sensory feedback through feedback from special nerves to achieve a stable improvement in brain function.
As for these professors, will they ask the classic question "If neurotechnology can decode consciousness and bidirectionally regulate, is it possible to intervene and change people's free will in the future?" after the investigation?
Gu Qing did not intend to argue with them.
After all, the application of this innovative neurotechnology in clinical neurosurgery, in addition to bringing these problems, is more important to save the dying and the wounded, and give those who are extremely eager for health and freedom a better future.
In this case, whoever dares to obstruct the implementation of technology will become the mortal enemy of all patients who pursue a better life.
Even if this person is a Western white left or the top of some industry...
And this research team composed of professors from major top hospitals, in the following days, from the initial surprise and discomfort, began to gradually keep up with the pace in a very short time.
I get up at 6:30 every day, and at 7:30 I start to learn about the application and development of technology under the leadership of several laboratory leaders in turn. In the afternoon, I start to study medical records and brief research reports, and study harder than high school students until late at night.
Then I go to the cafeteria to have a quick dinner, and then continue to study overtime voluntarily.
During this period, as a figure and senior who established the first multidisciplinary ischemic cerebrovascular disease treatment team in Daxia, Li Weijian has learned the identity of Professor Chen, the head of the applied neurotechnology laboratory, through communication.
Chen Qinghai, a proud student of his many years ago, but this student became silent after entering a large hospital and experiencing some dirty things.
Now it seems that this student is indeed better than his teacher, and he is doing very well in Jiuzhou Technology.
And Li Weijian also realized why he did not get in touch with this student in the past two years.
The results of these trillion-dollar investment projects of Jiuzhou Technology's Titanium Star Department, even if they are said to be shared, cannot really be taken for free. The extremely strict confidentiality work is definitely more stringent than that of his old troops.
However, as the investigation deepened, even though Li Weijian considered himself to be a conscious materialist warrior who had seen great storms, he still felt emotional many times.
"Why can Jiuzhou Technology be so concerned about these experimental projects? The results of projects with trillion-dollar investments can not only share data, but also share R&D personnel.
Those scientists and engineering teams can create huge value even if they focus on a project for a week, but how huge is the cost of doing so?
Moreover, Jiuzhou Technology's semiconductor department will actually customize the chip price for a small chip for experiment, as well as the coordination of system architecture and algorithm."
In the dead of night, Li Weijian closed his eyes and counted what he had seen and heard recently. He felt that Jiuzhou Technology was not like a private enterprise pursuing profits at all, but more like the unit where those great engineering warriors he had treated were located.
That young man named Gu has unknowingly mastered a huge amount of resources that even ordinary developed Guo Jia does not have.
Tens of thousands of graduate students, engineers, scientists, and an unknown number of trillions of project resources are all under the management of this young man, and are reasonably arranged and coordinated.
Such people are rare in the military field.
Li Weijian's emotion even gave him the urge to write a separate investigation report on Gu Qing after the mission was completed.
It is natural that in addition to him, a large number of people in the official research team have this idea.
Some people even want to resign from their original units and join Jiuzhou Technology Company.
This kind of scientific research environment with massive resources, responsiveness, and simple interpersonal communication is hard not to be tempted.
When people are immersed in something with full concentration, they will ignore the passage of time.
November 29th came suddenly.
On this day, Li Weijian got up early and went to the laboratory base to check medical records and research reports at 5:00 in the morning.
However, when he had just finished eating two steamed buns, changed into a lab coat and entered the core laboratory of the experimental base, he found that his student was already busy at the workbench.
Looking at the working status of the assistant beside him, they should have been working for a while.
Li Weijian did not disturb the other party's work. He stood outside the isolation window, like a student, concentrating on watching Chen Qinghai's every move.
Twenty years ago, he was a teacher, imparting knowledge without reservation at the podium and in the ward.
Twenty years later, he is a student, studying and exploring seriously outside the laboratory.
This morning self-study started very early, but there were no fewer students.
Experts from hospitals and institutions such as Daxia General Hospital, Neurological Medicine Research Institute of a certain hospital affiliated to Yanjing Medical University, First Affiliated Hospital of Daxia Medical University, Affiliated Hospital of Tongji University, Affiliated Hospital of Fudan University, West China Hospital of Xishu University, etc., as if they had made an appointment, came to this experimental base very early.
As usual, they were in the observation room observing the surgeries and experiments that the laboratory could show to the outside world.
Then came the exploration of drug medicine, the study of biological neural signal transmission, and the working principle of neural converters.
However, they did not go to the cafeteria for lunch as usual. They just ate some compressed biscuits at noon and continued to study non-stop.
Even if they learned the programming knowledge of Jiuzhou compiler in the afternoon...
But as one of the basic knowledge of Jiuzhou Technology's neural application technology, this group of old men and women were still unwilling to miss any learning opportunities.
Until the sunset, the official staff who accompanied them throughout the whole process informed the group of old students expressionlessly to pack their luggage, organize the materials, and go to another place for the next task.
In fact, without the official staff telling him, Li Weijian knew that the next task was not easy to do.
But when he was preparing his draft, every time he summarized a knowledge point, he would have a feeling.
This former student of his was already too far ahead in the professional path. If they study according to their research and development ideas, in the future, humans may really be able to achieve the level of immortality of the body if the consciousness is not dead.
Other medical professors also had similar feelings.
So a few days later, a bunch of research reports that were watched by countless people but destined to be seen by only a few people were presented to the desks of some people.
"Research Report on the Latest Scientific Research Results of the Applied Neurotechnology Laboratory of Jiuzhou Technology Brain Science Research Institute"
The name of this report is the most normal, but it was not put on the top, because the person who wrote this report was not very experienced and was not a professional. He was just a senior staff member with knowledge and resume who was inserted by the official.
And the top file bag contained Li Weijian's investigation report.
A pair of hands took it out and put it on the desk.
He opened it calmly and turned to the first page of the report. The words that came into view made this person's hands tremble subconsciously.
Of course, this was not an attack of Parkinson's disease, but a manifestation of subconscious shock of his own nerves.
"Report on the Feasibility of the Human Immortality Plan"
These words made this person's breathing a little tense.