Chapter Five Hundred: Convocation

? At the Capital Institute of Biogenetics, Wang Haoyi watched the news about the Reedman virus in his laboratory office, and thought from time to time.

This human disaster has lasted for several months, and the hardest-hit areas have become unimaginable.

Unfortunately, his research field is to establish and optimize gene editing technology in hematopoietic stem cells and T cells, to study the characteristics of related gene editing technology, and to improve the efficiency and specificity of genes. The main target area is genetic diseases.

This time, the Reedman virus belongs to virology, and it is not that serious in China, and they do not need to participate in the approach.

The virus has caused panic in the international community, but there is nothing he can do about it.

After reading the news, Wang Haoyi put down the newspaper and sighed. Worrying about other things is useless, and doing your own research is the point.

Boom! !

Just as Wang Haoyi was about to start researching his own subject, an old man with glasses knocked on the door and walked quickly to him, looking like he had something urgent.

"Director Liu, is there something urgent?"

"Academician Wang, the dean is here to inform that a breakthrough has been made in the Reedman virus vaccine in Tangshan, and urgent technical research is now underway, and experts in genomics are now needed."

Hearing this notice, Wang Haoyi suddenly stood up: "I'll go over."

Before Director Liu could speak again, Wang Haoyi had already started to pack up and was about to leave the office.

...

Donghai Institute of Life Sciences.

Yang Yunjia quickly entered the laboratory. In the laboratory, there were members of their team, as well as students and assistants.

Their team's key R&D plans are precision medicine research projects, epigenomics detection technology and clinical applications, and new technologies for RNA methylation epitranscriptomic sequencing, both of which are researched by him.

The hot Reedman virus outside belongs to immunology, but he is not an expert in immunology and virology, so he was not called by the medical team, and he continued to preside over their research at the research institute.

But just today, the capital came to inform that the Reedman virus vaccine in Tangshan has progressed, and experts from genomics experts are required to participate in urgent technical research.

"Mr. Yang, what happened?" Standing in the laboratory, other members and students all looked at him, and one student asked.

"The capital needs gene editing and genomics personnel to carry out urgent technical research. Yu Jun, Mi Shuangli, you two will come with me."

"Mr. Yang, is it convenient to say what technology is it?" asked a female researcher named Mi Shuangli.

"At the Tangshan Hospital in the capital, analyzing the genes of the Reedman virus vaccine."

"it is good."

The two nodded their heads and agreed without hesitation.

The Centers for Disease Control and Prevention issued a convening notice, and the experts and academicians in genomics and bioinformatics who are presiding over research projects across the country did not hesitate to agree to go to the capital Tangshan Hospital to carry out project research.

In just one day, nearly 20 experts and researchers in genomics have arrived in Tangshan.

The staff of the CDC and the Ministry of Health knew the importance of this project, coordinated in the center, quickly mobilized experimental equipment and materials, and prepared experimental conditions for researchers.

Tangshan Research Institute.

Chen Mo and Wu Bing, as well as the team members, entered the conference room.

Seeing a room full of people, several team members were surprised. Some of them have been recognized, including the expert academicians of genetic immunology that the medical team already has. There are 33 people on the field, almost including the top group of domestic genomics experts and academicians, including their former mentors.

It can be said that the most influential people in the field of genomics in China are all in this conference room.

They are looking at everyone, and the experts below are also looking at them. Seeing Chen Mo and Wu Bing leading the way, and the overly young team behind them, many people couldn't help but marvel.

It is this young team that has made a lot of achievements in two biological horrors, and this time it has made a breakthrough under the circumstances that they are not optimistic. Seeing that among the team members, there are students of their own, some academicians smile with satisfaction, at least their students are promising, and they are also very proud.

However, compared with Chen Mo, who took the lead, it seems that any genius has become bleak, and everyone's eyes quickly fell on Chen Mo.

In the past, I only heard his name but never saw him, but today I finally saw him.

Chen Mo also glanced at the experts and researchers on the field.

Their group can also find the poison protein, but in order to speed up the speed, the more people, the faster the speed. This time, the Centers for Disease Control and the Ministry of Health coordinated centrally, supported by the two hospitals, and found so many researchers, which was beyond his expectations.

After distributing all the materials, Chen Mocai walked to the podium in the conference room and directly entered the theme.

"This morning, we conducted another blood test on the patient, and you have the test results. The patient has regained initial consciousness, the antibody concentration in his body has increased compared with two days ago, and the number of viruses is decreasing. In theory, after five days or so, patients can develop resistance to Reedman virus."

After Chen Mo spoke, everyone listened carefully to Chen Mo's explanation. Many people on the field were old enough to be Chen Mo's teacher, but Chen Mo's performance was enough to be their teacher. The breakthrough of Reedman's virus vaccine was under the auspices of him, and no one dared to despise Chen Mo because of his age.

Hearing that the vaccine is effective, many people are still a little happy, but they are interrupted by Chen Mo just as they have some surprises.

"But we detected two toxic proteins in the patient's body, both of which also increased with the antibody concentration. Just two hours ago, the patient died in agony, less than five days later. He was not killed by the Reedman virus, but by a toxic protein in his body that killed him.

We preliminarily judged that this toxic protein was caused by the potential toxic protein gene in the mRNA of the vaccine platform system. So next, everyone's task is to find the two types of toxic protein genes in the vaccine, and we will find a way to knock out these two genes to remove the toxicity of the vaccine. "

"Academician Chen, is there any drug to degrade these two toxic proteins to achieve the purpose of treatment?"

Hearing the interrupted question below, Chen Mo nodded and replied: "We have thought about this method. The medical team is looking for a drug that degrades the toxin protein, but it has not been found so far, and it can also cure the symptoms but not the root cause."

"Academician Chen, is there a sample of toxic protein?" Yang Yunjia, who was sitting in the first row, asked.

"Yes, we have isolated some samples from the blood of patients, but not many. After the project starts, samples of toxic proteins will be distributed to various laboratories. Next, I will explain to you the relevant characteristics of toxic proteins and mRNA. Relevant information. If you have any questions, you can interrupt and ask me during the period, or ask Academician Wu, and we will try our best to answer you when conditions permit."

After the explanation, Chen Mo began to talk about some characteristics of the toxic protein, as well as information related to mRNA, so that they could start their research.